SMC1B Antibodies

AND SMC1B ELISA kits, SMC1B Proteins

Many biological assays use antibodies to detect SMC1B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SMC1B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SMC1B antibodies...

We validate the specificity of these antibodies to SMC1B by testing them on tissues known to express SMC1B positively and negatively. Browse below to find the SMC1B antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SMC1B Infographic by Boster Bio

All SMC1B Products

Product

Figures

Specificity

Applications

Price

Anti-SMC1B Antibody

Human

ELISA, WB

$380
Cat # A10280
100ul

SMC1L2 (SMC1B) (NM_148674) Human Over-expression Lysate

Human

$960
Cat # LS027127
100 µg

Anti-SMC1B Antibody Picoband™

Human, Mouse, Rat

ELISA, IF, ICC, WB

$370
Cat # A10280-1
100 µg/vial

SMC1B Overview

Facts about Structural maintenance of chromosomes protein 1B.

SMC1B 3D structure. Source: alphafold

Structural maintenance of chromosomes protein 1B (SMC1B)

Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its institution.

Contributes to axial element (AE) formation and the organization of chromatin loops across the AE. Plays a crucial role in synapsis, recombination and chromosome movements.

Gene Information

Human
Gene Name:	SMC1B
Uniprot:	Q8NDV3
Entrez:	27127

Family

Belongs to:

SMC family

Alternative Names

bK268H5; bK268H5.5; FLJ43748; mitosis-specific chromosome segregation protein like protein beta; SMC protein 1B; SMC1 (structural maintenance of chromosomes 1, yeast)-like 1; SMC1 structural maintenance of chromosomes 1-like 2 (yeast); SMC1 structural maintenance of chromosomes 1-like 2; SMC-1B; SMC1BETA; SMC-1-beta; SMC1L2; structural maintenance of chromosomes 1B; structural maintenance of chromosomes protein 1B

Molecular Weight

Mass (kDA):
143.908 kDA

Genomic Context


Human

Location:	22q13.31
Sequence:	22; NC_000022.11 (45344063..45413671, complement)

Subcellular Localizations

Nucleus. Chromosome. Chromosome, centromere. Associates with chromatin. In prophase I stage of meiosis, localizes along the AE of synaptonemal complexes. In late-pachytene-diplotene, the bulk of protein dissociates from the chromosome arms probably because of phosphorylation by PLK, except at centromeres, where cohesin complexes remain. Remains chromatin associated at the centromeres up to metaphase II. At anaphase II, dissociates from centromeres, allowing chromosomes segregation (By similarity).