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- Table of Contents
Facts about Cytohesin-4.
Promotes guanine-nucleotide exchange on ARF1 and ARF5.
Promotes the activation of ARF variables through replacement of GDP with GTP..
Human | |
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Gene Name: | CYTH4 |
Uniprot: | Q9UIA0 |
Entrez: | 27128 |
Belongs to: |
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No superfamily |
CYT4PH, SEC7 and coiled-coil domain-containing protein 4; cytohesin 4; cytohesin-4; pleckstrin homology, Sec7 and coiled/coil domains 4; pleckstrin homology, Sec7 and coiled-coil domains 4; PSCD4DJ63G5.1
Mass (kDA):
45.672 kDA
Human | |
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Location: | 22q13.1 |
Sequence: | 22; NC_000022.11 (37282508..37315341) |
Expressed predominantly in peripheral blood leukocytes.
Cell membrane; Peripheral membrane protein.
PMID: 10652308 by Ogasawara M., et al. Similarities in function and gene structure of cytohesin-4 and cytohesin-1, guanine nucleotide-exchange proteins for ADP-ribosylation factors.
PMID: 17398095 by Hofmann I., et al. The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane.