SLURP1 Antibodies

AND SLURP1 ELISA kits, SLURP1 Proteins

Many biological assays use antibodies to detect SLURP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLURP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLURP1 antibodies...

We validate the specificity of these antibodies to SLURP1 by testing them on tissues known to express SLURP1 positively and negatively. Browse below to find the SLURP1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLURP1 Infographic by Boster Bio

All SLURP1 Products

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Product

Figures

Specificity

Applications

Price

Anti-SLUR1 SLURP1 Antibody

Human

ELISA, WB

$380
Cat # A04970
100ul

SLURP1 (NM_020427) Human Over-expression Lysate

Human

$628
Cat # LS057152
100 µg

SLURP1 Overview

Facts about Secreted Ly-6/uPAR-related protein 1.

SLURP1 3D structure. Source: alphafold

Secreted Ly-6/uPAR-related protein 1 (SLURP1)

Has an antitumor action (PubMed:8742060). Was found to be a marker of late differentiation of the skin.

Implicated in keeping the physiological and structural integrity of the keratinocyte layers of the skin (PubMed:14721776, PubMed:17008884). In vitro down-regulates keratinocyte proliferation; the function may involve the projected role as modulator of nicotinic acetylcholine receptors (nAChRs) activity.

Gene Information

Human
Gene Name:	SLURP1
Uniprot:	P55000
Entrez:	57152

Family

Belongs to:

No superfamily

Alternative Names

ANUPARS(component B)-81/S; ARS Component B; ArsB; ARSlymphocyte antigen 6-like secreted; LY6LS; MDMsecreted Ly-6/uPAR-related protein 1; neoplastic urinary protein; secreted LY6/PLAUR domain containing 1; secreted Ly6/uPAR related protein 1; SLURP1; SLURP-1

Molecular Weight

Mass (kDA):
11.186 kDA

Genomic Context


Human

Location:	8q24.3
Sequence:	8; NC_000008.11 (142740949..142742406, complement)

Tissue Specificity

Granulocytes. Expressed in skin. Predominantly expressed in the granular layer of skin, notably the acrosyringium. Identified in several biological fluids such as sweat, saliva, tears, plasma and urine.

Subcellular Localizations

Secreted.

Diseases

Meleda Disease
Palmoplantar Keratosis
Keratosis
Pruritus
Liver Diseases
Hereditary Diseases
Common Wart
Melanoma
Keratitis
Hypoxia
Pachyonychia Congenita
Haploinsufficiency

Virus Diseases
Cholestasis
Lentigo
Tumor Angiogenesis
Corneal Diseases
Thickened Nails

Interacting Proteins

CHRNA7

Pathways

Cell Migration
Cell Death
Cell Development
Angiogenesis
Localization

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLURP1

References

PMID: 16354194 by Arredondo J., et al. Biological effects of SLURP-1 on human keratinocytes.

PMID: 8742060 by Ridge R.J., et al. Partial N-terminal amino acid sequence of the anti-neoplastic urinary protein (ANUP) and the anti-tumour effect of the N-terminal nonapeptide of the unique cytokine present in human granulocytes.