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- Table of Contents
Facts about Schlafen family member 13.
Does not act on tRNA(Sec) (PubMed:29563550). Able to restrict HIV-1 virus replication; ability to inhibit HIV-1 replication is dependent on endoribonuclease activity (PubMed:29563550).
Human | |
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Gene Name: | SLFN13 |
Uniprot: | Q68D06 |
Entrez: | 146857 |
Belongs to: |
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Schlafen family |
DKFZp666J196; DKFZp686I026; FLJ31952; schlafen family member 13; SLFN10
Mass (kDA):
102.045 kDA
Human | |
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Location: | 17q12 |
Sequence: | 17; NC_000017.11 (35435096..35451103, complement) |
Cytoplasm.
PMID: 29563550 by Yang J.Y., et al. Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control.