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- Table of Contents
Facts about Sodium/hydrogen exchanger 9.
Involved in organelle ion homeostasis by contributing to the maintenance of the distinctive acidic pH values of the Golgi and post-Golgi compartments in the cell. .
Human | |
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Gene Name: | SLC9A9 |
Uniprot: | Q8IVB4 |
Entrez: | 285195 |
Belongs to: |
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monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family |
AUTS16; FLJ35613; Na(+)/H(+) exchanger 9; NHE9; NHE-9; putative protein product of Nbla00118; sodium/hydrogen exchanger 9; sodium/proton exchanger NHE9; solute carrier family 9 (sodium/hydrogen exchanger); solute carrier family 9 (sodium/hydrogen exchanger), isoform 9; solute carrier family 9 (sodium/hydrogen exchanger), member 9; Solute carrier family 9 member 9
Mass (kDA):
72.565 kDA
Human | |
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Location: | 3q24 |
Sequence: | 3; NC_000003.12 (143265222..143848492, complement) |
Ubiquitously expressed in all tissues tested. Expressed at highest levels in heart and skeletal muscle, followed by placenta, kidney, and liver. Expressed in the brain, in the medulla and spinal cord.
Late endosome membrane; Multi-pass membrane protein.
PMID: 14569117 by De Silva M.G., et al. Disruption of a novel member of a sodium/hydrogen exchanger family and DOCK3 is associated with an attention deficit hyperactivity disorder-like phenotype.
PMID: 15522866 by Nakamura N., et al. Four Na+/H+ exchanger isoforms are distributed to Golgi and post- Golgi Compartments and are involved in organelle pH regulation.