SLC6A5 Antibodies

AND SLC6A5 ELISA kits, SLC6A5 Proteins

Many biological assays use antibodies to detect SLC6A5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC6A5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC6A5 antibodies...

We validate the specificity of these antibodies to SLC6A5 by testing them on tissues known to express SLC6A5 positively and negatively. Browse below to find the SLC6A5 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC6A5 Infographic by Boster Bio

All SLC6A5 Products

Product

Figures

Specificity

Applications

Price

Anti-SLC6A5 Antibody

Human, Mouse, Rat

$405
Cat # A03349
100ul

Anti-Glyt2 Rabbit Monoclonal Antibody

Human, Mouse, Rat

$370
Cat # M03349
100 μl/vial

Glyt2 (SLC6A5) (NM_004211) Human Over-expression Lysate

Human

$960
Cat # LS009152
100 µg

SLC6A5 Overview

Facts about Sodium- and chloride-dependent glycine transporter 2.

SLC6A5 3D structure. Source: alphafold

Sodium- and chloride-dependent glycine transporter 2 (SLC6A5)

Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May cause the termination of neurotransmission at strychnine-sensitive glycinergic synapses.

Gene Information

Human
Gene Name:	SLC6A5
Uniprot:	Q9Y345
Entrez:	9152

Family

Belongs to:

sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family

Alternative Names

Glycine Transporter-2; GlyT2; GLYT-2; GLYT2GlyT-2; HKPX3; NET1; SLC6A5; sodium- and chloride-dependent glycine transporter 2; solute carrier family 6 (neurotransmitter transporter, glycine), member 5; Solute carrier family 6 member 5

Molecular Weight

Mass (kDA):
87.434 kDA

Genomic Context


Human

Location:	11p15.1
Sequence:	11; NC_000011.10 (20599494..20659285)

Tissue Specificity

Expressed in medulla, and to a lesser extent in spinal cord and cerebellum.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Hyperexplexia
Muscle Hypertonia
Nervousness
Schizophrenia
Disease Of Adrenal Medulla
Pain
Apnea
Reflex, Abnormal
Nervous System Disorder
Ischemia
Neuralgia
Muscle Spasticity

Mutation, Out-of-frame
Spinal Cord Injuries
Varicosity
Amyotrophic Lateral Sclerosis
Spasm
Muscular Stiffness

Pathways

Transport
Localization
Glycine Transport
Synaptic Transmission
Exocytosis
Startle Response
Reflex
Translation
Locomotion
Pathogenesis
Innervation
Synapse Maturation
Cell Adhesion

Neuromuscular Junction Development
Proteolysis
Neurotransmitter Transport
Reverse Transcription
Sensitization
Axon Guidance
Cognition

PTMs

Phosphorylation
Reduction
Glycosylation

Ubiquitination
Biotinylation
Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC6A5

References

PMID: 9845349 by Morrow J.A., et al. Molecular cloning and functional expression of the human glycine transporter GlyT2 and chromosomal localisation of the gene in the human genome.

PMID: 10381548 by Gallagher M.J., et al. Characterization of multiple forms of the human glycine transporter type-2.