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- Table of Contents
Facts about Sodium/nucleoside cotransporter 2.
Plays a crucial role in specific uptake and salvage of purine nucleosides in kidney and other tissues. .
Human | |
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Gene Name: | SLC28A2 |
Uniprot: | O43868 |
Entrez: | 9153 |
Belongs to: |
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concentrative nucleoside transporter (CNT) (TC 2.A.41) family |
CNT2SPNT; Concentrative nucleoside transporter 2; FLJ21468; HCNT2; HsT17153; MGC138252; Na(+)/nucleoside cotransporter 2; sodium/nucleoside cotransporter 2; Sodium/purine nucleoside co-transporter; Sodium-coupled nucleoside transporter 2; solute carrier family 28 (sodium-coupled nucleoside transporter), member 2; Solute carrier family 28 member 2; SPNT1CNT 2
Mass (kDA):
71.926 kDA
Human | |
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Location: | 15q21.1 |
Sequence: | 15; NC_000015.10 (45252234..45277846) |
Expressed in heart and skeletal muscle followed by liver, kidney, intestine, pancreas, placenta and brain. Weak expression in lung.
Membrane; Multi-pass membrane protein.
PMID: 9435697 by Wang J., et al. Na+-dependent purine nucleoside transporter from human kidney: cloning and functional characterization.
PMID: 10087507 by Ritzel M.W.L., et al. Molecular cloning, functional expression and chromosomal localization of a cDNA encoding a human Na+/nucleoside cotransporter (hCNT2) selective for purine nucleosides and uridine.