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- Table of Contents
Facts about Large neutral amino acids transporter small subunit 3.
Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer. .
Human | |
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Gene Name: | SLC43A1 |
Uniprot: | O75387 |
Entrez: | 8501 |
Belongs to: |
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SLC43A transporter (TC 2.A.1.44) family |
LAT3prostate cancer overexpressed gene 1; PB39L-type amino acid transporter 3; POV1large neutral amino acids transporter small subunit 3; Prostate cancer overexpressed gene 1 protein; R00504; Solute carrier family 43 member 1; solute carrier family 43, member 1
Mass (kDA):
61.477 kDA
Human | |
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Location: | 11q12.1 |
Sequence: | 11; NC_000011.10 (57484531..57516561, complement) |
In adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells.
Membrane; Multi-pass membrane protein.
PMID: 9722952 by Cole K.A., et al. cDNA sequencing and analysis of POV1 (PB39): a novel gene up- regulated in prostate cancer.
PMID: 12930836 by Babu E., et al. Identification of a novel system L amino acid transporter structurally distinct from heterodimeric amino acid transporters.