SLC35D2 Antibodies

AND SLC35D2 ELISA kits, SLC35D2 Proteins

Many biological assays use antibodies to detect SLC35D2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC35D2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC35D2 antibodies...

We validate the specificity of these antibodies to SLC35D2 by testing them on tissues known to express SLC35D2 positively and negatively. Browse below to find the SLC35D2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC35D2 Infographic by Boster Bio

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Anti-SLC35D2 Antibody

Human

ELISA, ICC, WB

$449
Cat # A12449
0.1 mg

SLC35D2 Overview

Facts about UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter.

SLC35D2 3D structure. Source: alphafold

UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter (SLC35D2)

Antiporter transporting nucleotide sugars like UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP- mannose (GDP-Man) pooled from the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May participate in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling.

Gene Information

Human
Gene Name:	SLC35D2
Uniprot:	Q76EJ3
Entrez:	11046

Family

Belongs to:

TPT transporter family

Alternative Names

HFRC; HFRC1UDP-N-acetylglucosamine transporter; Homolog of Fringe connection protein 1; MGC117215; MGC142139; Solute carrier family 35 member D2; solute carrier family 35, member D2; SQV7Lfringe connection; SQV7-like protein; UDP-galactose transporter-related protein 8; UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter; UGTREL8; UGTrel8hfrc

Molecular Weight

Mass (kDA):
36.673 kDA

Genomic Context


Human

Location:	9q22.32
Sequence:	9; NC_000009.12 (96313437..96383711, complement)

Tissue Specificity

Highly expressed in heart, kidney, small intestine, placenta, lung and peripheral blood leukocyte. Weakly expressed in skeletal muscle and spleen. Not expressed in brain, colon and thymus.

Subcellular Localizations

Golgi apparatus membrane; Multi-pass membrane protein.

Diseases

Malignant Neoplasm Of Breast
Carcinoma

Pathways

Transport
Secretory Pathway
Reverse Transcription
Glycosylation
Localization

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC35D2

References

PMID: 15082721 by Suda T., et al. Molecular cloning and characterization of a human multisubstrate specific nucleotide-sugar transporter homologous to Drosophila fringe connection.

PMID: 15607426 by Ishida N., et al. Identification and characterization of human Golgi nucleotide sugar transporter SLC35D2, a novel member of the SLC35 nucleotide sugar transporter family.