SLC29A1 Antibodies

AND SLC29A1 ELISA kits, SLC29A1 Proteins

Many biological assays use antibodies to detect SLC29A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC29A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC29A1 antibodies...

We validate the specificity of these antibodies to SLC29A1 by testing them on tissues known to express SLC29A1 positively and negatively. Browse below to find the SLC29A1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC29A1 Infographic by Boster Bio

All SLC29A1 Products

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Product

Figures

Specificity

Applications

Price

Anti-SLC29A1 Antibody

Human

ELISA, IF, IHC-P, WB

$449
Cat # A02058
0.1 mg

Anti-SLC29A1 Antibody

Human, Mouse, Rat

$405
Cat # A02058-1
100ul

ENT1 (SLC29A1) (NM_001078177) Human Over-expression Lysate

Human

$628
Cat # LS002030
100 µg

SLC29A1 Overview

Facts about Equilibrative nucleoside transporter 1.

SLC29A1 3D structure. Source: alphafold

Equilibrative nucleoside transporter 1 (SLC29A1)

Mediates both influx and efflux of nucleosides throughout the membrane (equilibrative transporter). It's sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent.

It has a greater affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs).

Gene Information

Human
Gene Name:	SLC29A1
Uniprot:	Q99808
Entrez:	2030

Family

Belongs to:

SLC29A/ENT transporter (TC 2.A.57) family

Alternative Names

ENT1es-type; equilibrative nucleoside transporter 1; MGC1465; MGC3778; solute carrier family 29 (nucleoside transporters), member 1; Solute carrier family 29 member 1; solute carrier family 29, member 1

Molecular Weight

Mass (kDA):
50.219 kDA

Genomic Context


Human

Location:	6p21.1
Sequence:	6; NC_000006.12 (44219587..44234144)

Tissue Specificity

Detected in erythrocytes (at protein level). Expressed in heart, brain, mammary gland, erythrocytes and placenta, and also in fetal liver and spleen.

Subcellular Localizations

Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Predominantly localized in the basolateral membrane in polarized MDCK cells.

Diseases

Malignant Neoplasms
Neoplasms
Leukemia
Malignant Neoplasm Of Pancreas
Pancreatic Neoplasm
Adenocarcinoma
Congenital Dyserythropoietic Anemia
Leukemia, Myelocytic, Acute
Carcinoma
Myeloid Leukemia
Hypoxia
Diabetes Mellitus

Gestational Diabetes
Lymphoma
Pancreatic Adenocarcinoma
Malignant Neoplasm Of Lung
Mammary Neoplasms
Chronic Lymphocytic Leukemia
Acute Lymphocytic Leukemia

Pathways

Transport
Nucleoside Transport
Adenosine Transport
Localization
Drug Resistance
Cell Cycle
Uridine Transport
Nucleobase Transport
Drug Transport
Secretion
Reverse Transcription
Cell Proliferation

Cell Cycle Arrest
Nucleoside Salvage
Response To Ethanol
Clathrin-mediated Endocytosis
Regulation Of Nucleoside Transport
Aging
Response To Caffeine

PTMs

Phosphorylation
Biotinylation

Reduction
Deamination

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC29A1

References

PMID: 8986748 by Griffiths M., et al. Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs.

PMID: 10755314 by Lum P.Y., et al. Human intestinal es nucleoside transporter: molecular characterization and nucleoside inhibitory profiles.