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- Table of Contents
Facts about Protein 4.1.
It plays an integral role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes.
Human | |
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Gene Name: | EPB41 |
Uniprot: | P11171 |
Entrez: | 2035 |
Belongs to: |
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No superfamily |
4.1RBand 4.1; E41P; EL1; EPB4.1; erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked); erythrocyte surface protein band 4.1; HE; P4.1; protein 4.1
Mass (kDA):
97.017 kDA
Human | |
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Location: | 1p35.3 |
Sequence: | 1; NC_000001.11 (28887091..29120046) |
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Nucleus.
PMID: 3467321 by Conboy J.G., et al. Molecular cloning of protein 4.1, a major structural element of the human erythrocyte membrane skeleton.
PMID: 3223413 by Tang T.K., et al. Expression of specific isoforms of protein 4.1 in erythroid and non- erythroid tissues.