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- Table of Contents
Facts about Monocarboxylate transporter 11.
Probably involved in hepatic lipid metabolism: overexpression results in an increase of triacylglycerol(TAG) levels, modest increases in intracellular diacylglycerols and declines in lysophosphatidylcholine, cholesterol ester and sphingomyelin lipids (PubMed:24390345). .
Human | |
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Gene Name: | SLC16A11 |
Uniprot: | Q8NCK7 |
Entrez: | 162515 |
Belongs to: |
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major facilitator superfamily |
Monocarboxylate transporter 11
Mass (kDA):
47.791 kDA
Human | |
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Location: | 17p13.1 |
Sequence: | 17; NC_000017.11 (7041621..7044411, complement) |
Expressed in liver, salivary gland and thyroid.
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
PMID: 28666119 by Rusu V., et al. Type 2 diabetes variants disrupt function of SLC16A11 through two distinct mechanisms.