Protein shisa-6 Antibodies

AND Shisa6 ELISA kits, Protein shisa-6 Proteins

Many biological assays use antibodies to detect Protein shisa-6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein shisa-6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein shisa-6 antibodies...

We validate the specificity of these antibodies to Protein shisa-6 by testing them on tissues known to express Shisa6 positively and negatively. Browse below to find the Shisa6 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Shisa6 Infographic by Boster Bio

All Shisa6 Products

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Anti-SHISA6 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A14975-1
100 μg/vial

Shisa6 Overview

Facts about Protein shisa-6.

Protein shisa-6 (Shisa6)

Involved in maintenance of high-frequency synaptic transmission in hippocampal CA3-CA1 synapses. Regulates AMPA-type glutamate receptor (AMPAR) immobilization in postsynaptic density keeping the stations in an activated state in the presence of glutamate and preventing neurological depression (PubMed:26931375).

May play a role in self-renewal and differentiation of spermatogonial stem cells by inhibiting canonical Wnt signaling pathway (PubMed:28196692). .

Gene Information

Mouse
Gene Name:	Shisa6
Uniprot:	Q3UH99
Entrez:	380702

Family

Belongs to:

shisa family

Alternative Names

shisa homolog 6 (Xenopus laevis)

Molecular Weight

Mass (kDA):
58.426 kDA

Genomic Context


Mouse

Location:	11\|11 B3
Sequence:	11;

Tissue Specificity

Highly expressed in cerebellum and hippocampal neurons: CA1 stratum oriens and stratum radiatum, CA3 stratum oriens and stratum lucidum, and the dentate gyrus polymorphic layer (PubMed:26931375). Expressed in other brain structures including olfactory bulb, cortex, amigdala and midbrain (at protein level) (PubMed:26623514, PubMed:26931375). Also expressed in a subset of spermatogonial stem cells (PubMed:28196692). Also expressed in eye, heart, kidney, lung, muscle and spleen. Isoform 2: Specifically expressed in hippocampus (PubMed:26931375).

PTMs

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Shisa6

References

PMID: 26623514 by Farrow P., et al. Auxiliary subunits of the CKAMP family differentially modulate AMPA receptor properties.

PMID: 26931375 by Klaassen R.V., et al. Shisa6 traps AMPA receptors at postsynaptic sites and prevents their desensitization during synaptic activity.