Sh3pxd2b Antibodies

AND Sh3pxd2b ELISA kits, Sh3pxd2b Proteins

Many biological assays use antibodies to detect Sh3pxd2b, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sh3pxd2b in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sh3pxd2b antibodies...

We validate the specificity of these antibodies to Sh3pxd2b by testing them on tissues known to express Sh3pxd2b positively and negatively. Browse below to find the Sh3pxd2b antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Sh3pxd2b Infographic by Boster Bio

All Sh3pxd2b Products

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Product

Figures

Specificity

Applications

Price

SH3PXD2B (NM_001017995) Human Recombinant Protein

$1249
Cat # PROTA1X283
20 µg

Anti-SH3PXD2B Antibody (C-Term)

Human

Flow Cytometry, WB

$298
Cat # M08324
50 µl

SH3PXD2B (NM_001017995) Human Over-expression Lysate

Human

$960
Cat # LS285590
100 µg

Sh3pxd2b Overview

Facts about SH3 and PX domain-containing protein 2B.

SH3 and PX domain-containing protein 2B (Sh3pxd2b)

Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides.

Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation.

Gene Information

Mouse
Gene Name:	Sh3pxd2b
Uniprot:	A2AAY5
Entrez:	268396

Family

Belongs to:

SH3PXD2 family

Alternative Names

SH3 and PX domain-containing protein 2B

Molecular Weight

Mass (kDA):
101.517 kDA

Genomic Context


Mouse

Location:	11\|11 A4
Sequence:	11;

Tissue Specificity

Highly expressed in the stromal-vascular fraction of white adipose tissue with moderate expression in heart, skeletal muscle and the mature adipocyte fraction of white adipose tissue. Also expressed in brain, spleen, kidney and liver. Expressed in white and brown adipose tissues, eye, lung, heart, brain, spleen, stomach, liver and skeletal muscle (at protein level). Not expressed in kidney or bone marrow.

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Sh3pxd2b

References

PMID: 18959745 by Hishida T., et al. A novel gene, fad49, plays a crucial role in the immediate early stage of adipocyte differentiation via involvement in mitotic clonal expansion.

PMID: 19669234 by Mao M., et al. The podosomal-adaptor protein SH3PXD2B is essential for normal postnatal development.