Serpin B4 Antibodies

AND SERPINB4 ELISA kits, Serpin B4 Proteins

Many biological assays use antibodies to detect Serpin B4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Serpin B4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Serpin B4 antibodies...

We validate the specificity of these antibodies to Serpin B4 by testing them on tissues known to express SERPINB4 positively and negatively. Browse below to find the SERPINB4 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SERPINB4 Infographic by Boster Bio

All SERPINB4 Products

Product

Figures

Specificity

Applications

Price

Anti-Serpin B4 SERPINB4 Antibody

4 Q&As

Human

$360
Cat # A07524
100 µl

Anti-Serpin B4 SERPINB4 Antibody

Human, Mouse, Rat

ICC, WB

$405
Cat # A07524-1
100ul

Human Serpin B4 Recombinant Protein

SDS-PAGE

$250
Cat # PROTP48594
Starting from 10ug

Anti-SERPINB4 Mouse Monoclonal Antibody [Clone ID: OTI4C8]

Human

IHC, WB

$523
Cat # M07524
100 µl

SERPINB4 (NM_002974) Human Over-expression Lysate

Human

$628
Cat # LS006318
100 µg

SERPINB4 Overview

Facts about Serpin B4.

SERPINB4 3D structure. Source: alphafold

Serpin B4 (SERPINB4)

May act as a protease inhibitor to modulate the host immune response against tumor cells. .

Gene Information

Human
Gene Name:	SERPINB4
Uniprot:	P48594
Entrez:	6318

Family

Belongs to:

serpin family

Alternative Names

LEUPIN; Peptidase Inhibitor 11; PI11; PI-11; PI11clade B (ovalbumin), member 4; SCCA2; Serpin B4; serpin peptidase inhibitor, clade B (ovalbumin), member 4; SerpinB4; squamous cell carcinoma antigen 1; Squamous cell carcinoma antigen 2

Molecular Weight

Mass (kDA):
44.854 kDA

Genomic Context


Human

Location:	18q21.33
Sequence:	18; NC_000018.10 (63637259..63644310, complement)

Tissue Specificity

Squamous cells.

Subcellular Localizations

Cytoplasm. Seems to also be secreted in plasma by cancerous cells but at a low level.

Diseases

Carcinoma
Malignant Squamous Cell Neoplasm
Neoplasms
Asthma
Inflammation
Liver Diseases
Urinary Stress Incontinence
Abscess
Hepatitis, Chronic
Vertigo
Disseminated Malignant Neoplasm
Conductive Hearing Loss

Mouth Neoplasms
Malignant Neoplasms
Cholesteatoma
Erythroblastosis
Infective Disorder
Psoriasis
Liver Carcinoma

Pathways

Keratinocyte Differentiation
Transport
Cell Adhesion
Sensitization
Reverse Transcription
Cell Death
Proteolysis
Immune Response

Cell Growth
Cell Communication
Defense Response

PTMs

Cleavage

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SERPINB4

References

PMID: 7589435 by Barnes R.C., et al. Identification of a novel human serpin gene; cloning sequencing and expression of leupin.

PMID: 7724531 by Schneider S.S., et al. A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene.