Acyl-CoA desaturase Antibodies

AND SCD ELISA kits, Acyl-CoA desaturase Proteins

Many biological assays use antibodies to detect Acyl-CoA desaturase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Acyl-CoA desaturase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Acyl-CoA desaturase antibodies...

We validate the specificity of these antibodies to Acyl-CoA desaturase by testing them on tissues known to express SCD positively and negatively. Browse below to find the SCD antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SCD Infographic by Boster Bio

All SCD Products

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Anti-Acyl-CoA desaturase SCD Antibody

Human, Mouse, Rat

$405
Cat # A00588
100ul

SCD1 (SCD) (NM_005063) Human Over-expression Lysate

Human

$628
Cat # LS006319
100 µg

Anti-SCD Antibody Picoband®

Human

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A00588-1
100 µg/vial

Anti-SCD Antibody Picoband®

Human

ELISA, Flow Cytometry, IP, IF, ICC, WB

$370
Cat # A00588-2
100 μg/vial

SCD Overview

Facts about Acyl-CoA desaturase.

SCD 3D structure. Source: alphafold

Acyl-CoA desaturase (SCD)

Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to present the first double bond into saturated fatty acyl-CoA substrates (PubMed:15907797, PubMed:18765284). Catalyzes the insertion of a cis double bond in the delta-9 place into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:15907797, PubMed:18765284).

Gives rise to a mix of 16:1 and 18:1 unsaturated fatty acids (PubMed:15610069). Plays an essential role in lipid biosynthesis.

Gene Information

Human
Gene Name:	SCD
Uniprot:	O00767
Entrez:	6319

Family

Belongs to:

fatty acid desaturase type 1 family

Alternative Names

FADS5; MSTP008; SCD1; SCD-1; SCDOS; Stearoyl-CoA desaturase

Molecular Weight

Mass (kDA):
41.523 kDA

Genomic Context


Human

Location:	10q24.31
Sequence:	10; NC_000010.11 (100347233..100364826)

Tissue Specificity

Detected in fetal liver, lung and brain. Highly expressed in adult adipose tissue, and at lower levels in adult brain and lung.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Anemia, Sickle Cell
Sudden Cardiac Death
Cardiac Death
Cardiac Arrhythmia
Infarction
Pain
Heart Diseases
Anemia
Myocardial Infarction
Cerebrovascular Accident
Cardiomyopathies
Tachycardia, Ventricular
Hypertensive Disease

Sudden Death
Heart Failure
Coronary Heart Disease
Cardiac Fibrillation
Malignant Neoplasms
Hypertrophy
Diabetes Mellitus

Pathways

Pathogenesis
Dehiscence
Coagulation
Cell Adhesion
Transport
Secretion
Glomerular Filtration
Cell Cycle
Fatty Acid Oxidation
Lactation
Cell Proliferation
Aging
Localization

Excretion
Segmentation
Fertilization
Translation
Cell Death
Inflammatory Response
Metaphase

PTMs

Phosphorylation
Oxidation
Cleavage
Methylation
Nitration
Deacetylation
Sulphation

Carboxylation
Dephosphorylation
Acylation
Sulphonation
Biotinylation
Glycosylation
Acetylation

Palmitoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SCD

References

PMID: 10229681 by Zhang L., et al. Human stearoyl-CoA desaturase: alternative transcripts generated from a single gene by usage of tandem polyadenylation sites.

PMID: 11415448 by Zhang L., et al. Isolation and characterization of the human stearoyl-CoA desaturase gene promoter: requirement of a conserved CCAAT cis-element.