Protein sidekick-2 Antibodies

AND SDK2 ELISA kits, Protein sidekick-2 Proteins

Many biological assays use antibodies to detect Protein sidekick-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein sidekick-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein sidekick-2 antibodies...

We validate the specificity of these antibodies to Protein sidekick-2 by testing them on tissues known to express SDK2 positively and negatively. Browse below to find the SDK2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SDK2 Infographic by Boster Bio

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SDK2 (NM_001144952) Human Recombinant Protein

$1249
Cat # PROTQ58EX2
20 µg

SDK2 Overview

Facts about Protein sidekick-2.

SDK2 3D structure. Source: alphafold

Protein sidekick-2 (SDK2)

Adhesion molecule that promotes lamina-specific synaptic connections in the retina and is specifically required for the formation of neuronal circuits that detect motion. Acts by promoting formation of synapses between two specific retinal cell types: the retinal ganglion cells W3B-RGCs as well as the excitatory amacrine cells VG3-ACs.

Formation of synapses between both of these cells plays a key role in detection of motion. Promotes synaptic connectivity via homophilic interactions.

Gene Information

Human
Gene Name:	SDK2
Uniprot:	Q58EX2
Entrez:	54549

Family

Belongs to:

sidekick family

Alternative Names

Protein sidekick-2

Molecular Weight

Mass (kDA):
239.396 kDA

Genomic Context


Human

Location:	17q25.1
Sequence:	17; NC_000017.11 (73334384..73644481, complement)

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein. Cell junction, synapse.

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SDK2

References

PMID: 28397838 by Harripaul R., et al. Mapping autosomal recessive intellectual disability: combined microarray and exome sequencing identifies 26 novel candidate genes in 192 consanguineous families.