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- Table of Contents
Facts about SCY1-like protein 2.
According to PubMed:16914521, has no detectable kinase activity in vitro. May regulate clathrin-dependent trafficking between the TGN and/or the endosomal system.
Human | |
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Gene Name: | SCYL2 |
Uniprot: | Q6P3W7 |
Entrez: | 55681 |
Belongs to: |
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protein kinase superfamily |
CVAK104; FLJ10074; KIAA1360Coated vesicle-associated kinase of 104 kDa; SCY1-like 2 (S. cerevisiae); SCY1-like protein 2
Mass (kDA):
103.709 kDA
Human | |
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Location: | 12q23.1 |
Sequence: | 12; NC_000012.12 (100267140..100341724) |
Cytoplasm, perinuclear region. Cytoplasmic vesicle, clathrin-coated vesicle. Golgi apparatus, trans-Golgi network membrane. Endosome membrane. According to PubMed:15809293, plasma membrane-associated in clathrin-coated vesicles. According to PubMed:16914521, colocalizes to the trans-Golgi network (TGN) and to endosomal membranes with clathrin, transferrin and plasma membrane adapter AP1 and AP3 complexes.
PMID: 15809293 by Conner S.D., et al. CVAK104 is a novel poly-L-lysine-stimulated kinase that targets the beta2-subunit of AP2.
PMID: 16914521 by Duewel M., et al. Clathrin-dependent association of CVAK104 with endosomes and the trans-Golgi network.