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- Table of Contents
10 Citations 9 Q&As
7 Citations 8 Q&As
Facts about Resistin.
Promotes chemotaxis in myeloid cells (PubMed:15064728). .
Human | |
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Gene Name: | RETN |
Uniprot: | Q9HD89 |
Entrez: | 56729 |
Belongs to: |
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resistin/FIZZ family |
Adipose tissue-specific secretory factor; ADSF; ADSFMGC126609; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich proteinprecursor 1; C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; Cysteine-rich secreted protein A12-alpha-like 2; Cysteine-rich secreted protein FIZZ3; FIZZ3; FIZZ3MGC126603; found in inflammatory zone 3; HXCP1; Resistin; RETN; RETN1; RSTNXCP1
Mass (kDA):
11.419 kDA
Human | |
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Location: | 19p13.2 |
Sequence: | 19; NC_000019.10 (7669049..7670455) |
Expressed in white adipose tissue (at protein level) (PubMed:11201732). Widely expressed, with particularly strong expression in lung, bone marrow, breast and peripheral blood (PubMed:15248836). Expressed strongly in bone marrow and at lower levels in lung, but not detected in other tissues (PubMed:15064728). Isoform 2 is detected in adipose tissue, bone marrow, brain, lung, peripheral blood, placenta and thymus (PubMed:15248836).
Secreted.
PMID: 10921885 by Holcomb I.N., et al. FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family.
PMID: 11201732 by Steppan C.M., et al. The hormone resistin links obesity to diabetes.
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