Protein CBFA2T1 (RUNX1T1)

Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of additional corepressors and histone-modifying enzymes (PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner (PubMed:23251453).

Can repress transactivation mediated by TCF12 (PubMed:16803958). Acts as a negative regulator of adipogenesis (By similarity).