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- Table of Contents
Facts about RUN domain-containing protein 3B.
Human | |
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Gene Name: | RUNDC3B |
Uniprot: | Q96NL0 |
Entrez: | 154661 |
Belongs to: |
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RUNDC3 family |
Rap2 binding protein 9; Rap2-binding protein 9; Rap2-interacting protein 9; RPIB9FLJ30671; RPIP-9; RPIP9MGC26655; RUN domain containing 3B; RUN domain-containing protein 3B
Mass (kDA):
52.813 kDA
Human | |
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Location: | 7q21.12 |
Sequence: | 7; NC_000007.14 (87627656..87832296) |
Isoform 2 is expressed at high levels in brain, thymus, ovary, testis, leukocyte, liver, small intestine and prostate. Isoform 1 is expressed in the brain, testis and adrenal gland. It is activated in tumorigenic breast cancer cell lines and in the primary tumor of breast cancer patients. Activation also correlates with metastatic lymph node invasion and can be detected in metastatic epithelial cells from the lymph nodes and in the bone marrow of patients.
PMID: 12645870 by Wang S., et al. Cloning, expression, and genomic structure of a novel human Rap2 interacting gene (RPIP9).
PMID: 15986426 by Raguz S., et al. Expression of RPIP9 (Rap2 interacting protein 9) is activated in breast carcinoma and correlates with a poor prognosis.