Rhotekin Antibodies

AND RTKN ELISA kits, Rhotekin Proteins

Many biological assays use antibodies to detect Rhotekin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Rhotekin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Rhotekin antibodies...

We validate the specificity of these antibodies to Rhotekin by testing them on tissues known to express RTKN positively and negatively. Browse below to find the RTKN antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RTKN Infographic by Boster Bio

All RTKN Products

Product

Figures

Specificity

Applications

Price

Anti-Rhotekin RTKN Antibody

Human, Mouse, Rat

$405
Cat # A07596
100ul

Anti-Rhotekin RTKN Antibody

Human, Mouse, Rat

ELISA, IHC

$380
Cat # A07596-1
100ul

RTKN (NM_001015055) Human Recombinant Protein

$1249
Cat # PROTQ9BST9
20 µg

Anti-RTKN Mouse Monoclonal Antibody [Clone ID: OTI1A4]

Human, Mouse, Rat

IF, IHC, WB

$523
Cat # M07596
100 µl

Anti-RTKN Mouse Monoclonal Antibody [Clone ID: OTI2E9]

Human, Mouse, Rat

IHC, WB

$523
Cat # M07596-1
100 µl

RTKN (NM_033046) Human Over-expression Lysate

Human

$628
Cat # LS006242
100 µg

Anti-RTKN Antibody Picoband™

Human

ELISA, Flow Cytometry, WB

$370
Cat # A07596-2
100 µg/vial

RTKN Overview

Facts about Rhotekin.

RTKN 3D structure. Source: alphafold

Rhotekin (RTKN)

Mediates Rho signaling to trigger NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. May play a novel role in the business of septin structures.

Gene Information

Human
Gene Name:	RTKN
Uniprot:	Q9BST9
Entrez:	6242

Family

Belongs to:

No superfamily

Alternative Names

B5; rhotekin; RTKN1

Molecular Weight

Mass (kDA):
62.667 kDA

Genomic Context


Human

Location:	2p13.1
Sequence:	2; NC_000002.12 (74425835..74441937, complement)

Tissue Specificity

Highly expressed in prostate, moderately in kidney, heart, brain, spleen, testis, placenta, small intestine, pancreas, skeletal muscle and peripheral blood leukocytes, and weakly in ovary, colon and thymus. Weakly expressed in all normal cell lines tested. Overexpressed in various cancer cell lines.

Diseases

Malignant Neoplasms
Neoplasms
Tissue Adhesions
Neoplasm Metastasis
Carcinogenesis
Carcinoma
Adenocarcinoma
Malignant Neoplasm Of Stomach
Cell Invasion
Neuroblastoma
Cell Transformation, Neoplastic
Carcinoma, Transitional Cell
Stomach Neoplasms

Tongue Neoplasms
Malignant Neoplasm Of Tongue
Metastatic Malignant Neoplasm To The Lymph Node
Tumor Progression
Malignant Neoplasm Of Breast
Colonic Neoplasms
Neoplasms, Experimental

Interacting Proteins

RHOA
Rhoa
SORBS3

Pathways

Localization
Cell Growth
Cell Migration
Gastrulation
Cell Proliferation
Muscle Cell Differentiation
Receptor Clustering
Mitosis
Prenylation
Virulence
Cytokinesis
Cell Division
Axon Extension

Translation
Cell Cycle
Cell Differentiation
Angiogenesis
Pathogenesis
Smooth Muscle Cell Differentiation
Bone Resorption

PTMs

Phosphorylation
Cleavage

Amidation
Prenylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RTKN

References

PMID: 10873388 by Fu Q., et al. Molecular cloning, expression characterization, and mapping of a novel putative inhibitor of rho GTPase activity, RTKN, to D2S145- D2S286.

PMID: 10940294 by Reynaud C., et al. The PDZ protein TIP-1 interacts with the Rho effector rhotekin and is involved in Rho signaling to the serum response element.