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- Table of Contents
Facts about Regulatory solute carrier protein family 1 member 1.
Also involved in transcriptional regulation of SLC22A2. Exhibits glucose-dependent, short-term inhibition of SLC5A1 and SLC22A2 by inhibiting the release of vesicles from the trans-Golgi network.
Human | |
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Gene Name: | RSC1A1 |
Uniprot: | Q92681 |
Entrez: | 6248 |
Belongs to: |
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No superfamily |
hRS1; regulatory solute carrier protein family 1 member 1; regulatory solute carrier protein, family 1, member 1; RS1Transporter regulator RS1
Mass (kDA):
66.79 kDA
Human | |
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Location: | 1p36.21 |
Sequence: | 1; NC_000001.11 (15659713..15662030) |
Expressed in small intestine, kidney and brain.
Cell membrane. Nucleus. Golgi apparatus, trans-Golgi network. Localizes at the inner side of the plasma membrane.
PMID: 8836035 by Lambotte S., et al. The human gene of a protein that modifies Na(+)-D-glucose co- transport.
PMID: 14724758 by Veyhl M., et al. Downregulation of the Na(+)- D-glucose cotransporter SGLT1 by protein RS1 (RSC1A1) is dependent on dynamin and protein kinase C.