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- Table of Contents
Facts about R-spondin-4.
Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. .
Mouse | |
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Gene Name: | Rspo4 |
Uniprot: | Q8BJ73 |
Entrez: | 228770 |
Belongs to: |
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R-spondin family |
C20orf182; chromosome 20 open reading frame 182; Cristin 4; CRISTIN4; dJ824F16.3; FLJ16018; hRspo4; Roof plate-specific spondin-4; RSPO4; RSpondin 4; R-Spondin 4; R-spondin family, member 4; R-spondin-4
Mass (kDA):
25.866 kDA
Mouse | |
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Location: | 2|2 G3 |
Sequence: | 2; |
PMID: 21693646 by Carmon K.S., et al. R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling.