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- Table of Contents
Facts about Ras-related GTP-binding protein C.
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Mouse | |
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Gene Name: | Rragc |
Uniprot: | Q99K70 |
Entrez: | 54170 |
Belongs to: |
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GTR/RAG GTP-binding protein family |
FLJ13311; GTPase-interacting protein 2; GTR2; Rag C protein; Rag C; RAGC; Ras-related GTP binding C; ras-related GTP-binding protein C; TIB929
Mass (kDA):
44.121 kDA
Mouse | |
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Location: | 4|4 D2.2 |
Sequence: | 4; |
Expressed most abundantly in kidney. Moderately expressed in brain, ovary, and testis, and detected at lower levels in heart, liver, and muscle. Not detected in lung, spleen, and small intestine. Widely expressed in tumor cells, with expression being specifically up-regulated in highly metastatic cells.
PMID: 10660099 by Nakaji T., et al. A new member of the GTPase superfamily that is upregulated in highly metastatic cells.
PMID: 25259925 by Peng M., et al. Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling.