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RPA2 Antibodies
AND RPA2 ELISA kits, RPA2 Proteins
Many biological assays use antibodies to detect RPA2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RPA2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RPA2 antibodies...
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RPA2 Infographic by Boster Bio
All RPA2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IP, WB
$370
Cat # P02067-1
100 μl
Cat # P02067-1
100 μl
Human, Mouse
ELISA
$480
Cat # EKC1503
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1503
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse
ELISA
$540
Cat # EKC2271
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2271
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2623
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2623
1 kit, containing two 96-well plates and all necessary reagents
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02067-1
100 μg/vial
Cat # A02067-1
100 μg/vial
Dog, Human, Monkey, Mouse, Rat
Flow Cytometry, IP, IF, IHC, WB
$523
Cat # M02067-1
100 µl
Cat # M02067-1
100 µl
Human, Monkey, Mouse, Rat
Flow Cytometry, IP, IF, IHC, WB
$523
Cat # M02067
100 µl
Cat # M02067
100 µl
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M02067-2
100 μg/vial
Cat # M02067-2
100 μg/vial
RPA2 Overview
Facts about Replication protein A 32 kDa subunit.
Replication protein A 32 kDa subunit (RPA2)
As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism.
Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. From the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation.
Gene Information
| Human | |
|---|---|
| Gene Name: | RPA2 |
| Uniprot: | P15927 |
| Entrez: | 6118 |
Family
| Belongs to: |
|---|
| replication factor A protein 2 family |
Alternative Names
REPA2; Replication factor A protein 2; replication protein A 32 kDa subunit; Replication protein A 34 kDa subunit; replication protein A2 (32kD); replication protein A2, 32kDa; RF-A protein 2; RP-A p32; RP-A p34; RPA2; RPA32; RPA34
Molecular Weight
Mass (kDA):
29.247 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p35.3 |
| Sequence: | 1; NC_000001.11 (27891524..27914797, complement) |
Subcellular Localizations
Nucleus. Nucleus, PML body. Redistributes to discrete nuclear foci upon DNA damage in an ATR-dependent manner.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Genotoxic Stress
- Ataxia Telangiectasia
- Carcinogenesis
- Malignant Squamous Cell Neoplasm
- Ataxia
- Multiple Endocrine Neoplasia Type 1
- Cell Transformation, Neoplastic
- Xeroderma Pigmentosum
- Endocrine Gland Neoplasms
- Hyperplasia
Interacting Proteins
- CDC45
- EIF4EBP3
- GAPDH
- RPA1
- RPA3
- SERTAD3
- SMARCAL1
- TIPIN
- UNG
- XPA
Pathways
- Dna Replication
- Dna Repair
- Cell Cycle
- Hyperphosphorylation
- Localization
- S Phase
- Telomere Maintenance
- Mitosis
- Cell Proliferation
- Cell Cycle Arrest
- Cell Growth
- Single-stranded Dna Binding
- Dna Methylation
PTMs
- Phosphorylation
- Cleavage
- Dephosphorylation
Research Areas
- Phospho-Specific
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RPA2
bosterbio.com/bosterbio-gene-info-cards/RPA2
References
PMID: 2406247 by Erdile L.F., et al. The primary structure of the 32-kDa subunit of human replication protein A.
PMID: 2200738 by Din S., et al. Cell-cycle-regulated phosphorylation of DNA replication factor A from human and yeast cells.