Roundabout homolog 4 Antibodies

AND ROBO4 ELISA kits, Roundabout homolog 4 Proteins

Many biological assays use antibodies to detect Roundabout homolog 4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Roundabout homolog 4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Roundabout homolog 4 antibodies...

We validate the specificity of these antibodies to Roundabout homolog 4 by testing them on tissues known to express ROBO4 positively and negatively. Browse below to find the ROBO4 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ROBO4 Infographic by Boster Bio

All ROBO4 Products

Product

Figures

Specificity

Applications

Price

Anti-Roundabout homolog 4 ROBO4 Antibody

Human

$405
Cat # A04479
100ul

Anti-Roundabout homolog 4 ROBO4 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A04479-1
100ul

Anti-ROBO4 Mouse Monoclonal Antibody [Clone ID: OTI4E2]

Human

$523
Cat # M04479
100 µl

ROBO4 (NM_019055) Human Over-expression Lysate

Human

$628
Cat # LS054538
100 µg

Anti-ROBO4 Antibody Picoband™

Human, Mouse, Rat

ELISA, WB

$370
Cat # A04479-2
100 µg/vial

ROBO4 Overview

Facts about Roundabout homolog 4.

ROBO4 3D structure. Source: alphafold

Roundabout homolog 4 (ROBO4)

Receptor for Slit proteins, at least for SLIT2, and appears to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins (By similarity).

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Gene Information

Human
Gene Name:	ROBO4
Uniprot:	Q8WZ75
Entrez:	54538

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

ECSM4; FLJ20798; Magic roundabout; MGC133352; MGC133353; MRB; ROBO4; roundabout homolog 4; roundabout homolog 4, magic roundabout (Drosophila)

Molecular Weight

Mass (kDA):
107.457 kDA

Genomic Context


Human

Location:	11q24.2
Sequence:	11; NC_000011.10 (124883691..124897865, complement)

Tissue Specificity

Specifically expressed in endothelial cells. Expressed at sites of angiogenesis in different tumor types.

Diseases

Tumor Angiogenesis
Pathologic Neovascularization
Neoplasms
Nervousness
Malignant Neoplasms
Hypoxia
Retinal Diseases
Neoplasm Metastasis
Carcinoma
Retinal Neovascularization
Systemic Infection
Influenza In Birds

Ovarian Neoplasm
Influenza
Retinopathy Of Prematurity
Malignant Neoplasm Of Ovary
Anoxia
Corneal Neovascularization

Pathways

Angiogenesis
Cell Migration
Axon Guidance
Endothelial Cell Migration
Tube Formation
Chemotaxis
Cell Proliferation
Cell Adhesion
Neurogenesis
Vasculogenesis
Localization
Leukocyte Chemotaxis
Pathogenesis

Transport
Muscle Cell Migration
Fertilization
Immune Response
System Development
Cell Motility
Innate Immune Response

PTMs

Phosphorylation

Methylation

Ribosylation

Research Areas

Angiogenesis
Cancer
Extracellular Matrix
Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ROBO4

References

PMID: 11944987 by Huminiecki L., et al. Magic roundabout is a new member of the roundabout receptor family that is endothelial specific and expressed at sites of active angiogenesis.