RNF40 Antibodies

AND RNF40 ELISA kits, RNF40 Proteins

Many biological assays use antibodies to detect RNF40, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RNF40 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RNF40 antibodies...

We validate the specificity of these antibodies to RNF40 by testing them on tissues known to express RNF40 positively and negatively. Browse below to find the RNF40 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RNF40 Infographic by Boster Bio

All RNF40 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-RNF40 Antibody

Human

IHC, WB

$405
Cat # A06979
100ul

Anti-RNF40 Antibody

Human, Mouse, Rat

IP, IHC, WB

$405
Cat # A06979-1
100ul

Anti-RNF40 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IP, IHC, WB

$370
Cat # M06979-1
100 μl/vial

RNF40 (NM_014771) Human Over-expression Lysate

Human

$628
Cat # LS009810
100 µg

Anti-RNF40 Antibody Picoband®

Human

ELISA, IF, IHC, WB

$370
Cat # A06979-2
100 µg/vial

RNF40 Overview

Facts about E3 ubiquitin-protein ligase BRE1B.

RNF40 3D structure. Source: alphafold

E3 ubiquitin-protein ligase BRE1B (RNF40)

Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively).

It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports regarding the cooperation with UBE2E1/UBCH are contradictory.

Gene Information

Human
Gene Name:	RNF40
Uniprot:	O75150
Entrez:	9810

Family

Belongs to:

BRE1 family

Alternative Names

95 kDa retinoblastoma-associated protein; BRE1-B; BRE1BMGC13051; EC 6.3.2,95 kDa retinoblastoma protein binding protein; EC 6.3.2.-; KIAA0661BRE1 E3 ubiquitin ligase homolog B; Rb-associated protein; RBP95E3 ubiquitin-protein ligase BRE1B; ring finger protein 40DKFZp686K191; STARING

Molecular Weight

Mass (kDA):
113.678 kDA

Genomic Context


Human

Location:	16p11.2
Sequence:	16; NC_000016.10 (30761612..30800231)

Tissue Specificity

Ubiquitously expressed. Expressed at higher level in testis, heart and pancreas, while it is only weakly expressed in lung, skeletal muscle and small intestine.