RNF157 Antibodies

AND RNF157 ELISA kits, RNF157 Proteins

Many biological assays use antibodies to detect RNF157, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RNF157 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RNF157 antibodies...

We validate the specificity of these antibodies to RNF157 by testing them on tissues known to express RNF157 positively and negatively. Browse below to find the RNF157 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RNF157 Infographic by Boster Bio

All RNF157 Products

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Price

RNF157 (NM_052916) Human Recombinant Protein

$1249
Cat # PROTQ96PX1
20 µg

RNF157 Overview

Facts about E3 ubiquitin ligase RNF157.

RNF157 3D structure. Source: alphafold

E3 ubiquitin ligase RNF157 (RNF157)

E3 ubiquitin ligase that ubiquitinates APBB1 for its degradation by the proteasome and so prevents apoptosis and promotes survival of neurons (PubMed:25342469). Has a dual role in neurons as it's also required for dendrite growth and maintenance for which its ligase activity isn't critical (PubMed:25342469).

May act as a scaffold molecule to modulate this procedure (PubMed:25342469). Acts as a downstream effector of the interconnected PI3K and MAPK signaling pathways and so participates in the regulation of the cell cycle (PubMed:28655764).

Gene Information

Human
Gene Name:	RNF157
Uniprot:	Q96PX1
Entrez:	114804

Family

Belongs to:

No superfamily

Alternative Names

KIAA1917; ring finger protein 157

Molecular Weight

Mass (kDA):
73.579 kDA

Genomic Context


Human

Location:	17q25.1
Sequence:	17; NC_000017.11 (76142456..76240493, complement)

Subcellular Localizations

Cytoplasm.

PTMs

Lipoprotein

Myristate

Phosphoprotein

Research Areas

Zinc Finger

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RNF157

References

PMID: 20213681 by Suzuki T., et al. Strategy for comprehensive identification of human N-myristoylated proteins using an insect cell-free protein synthesis system.

PMID: 25342469 by Matz A., et al. Regulation of neuronal survival and morphology by the E3 ubiquitin ligase RNF157.