RNF152 Antibodies

AND RNF152 ELISA kits, RNF152 Proteins

Many biological assays use antibodies to detect RNF152, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RNF152 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RNF152 antibodies...

We validate the specificity of these antibodies to RNF152 by testing them on tissues known to express RNF152 positively and negatively. Browse below to find the RNF152 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RNF152 Infographic by Boster Bio

All RNF152 Products

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Product

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Specificity

Applications

Price

Anti-RNF152 Antibody

Rat

$405
Cat # A12023
100ul

RNF152 (NM_173557) Human Over-expression Lysate

Human

$628
Cat # LS220441
100 µg

RNF152 Overview

Facts about E3 ubiquitin-protein ligase RNF152.

RNF152 3D structure. Source: alphafold

E3 ubiquitin-protein ligase RNF152 (RNF152)

E3 ubiquitin-protein ligase mediating 'Lys-63'-linked polyubiquitination of RRAGA in response to amino acid starvation. Thereby, regulates mTORC1 signaling and plays a role in the cellular response to amino acid availability (PubMed:25936802).

Also mediates 'Lys-48'-linked polyubiquitination of target proteins and their subsequent targeting to the proteasome for degradation. Induces apoptosis when overexpressed (PubMed:21203937).

Gene Information

Human
Gene Name:	RNF152
Uniprot:	Q8N8N0
Entrez:	220441

Family

Belongs to:

RNF152 family

Alternative Names

E3 ubiquitin-protein ligase RNF152

Molecular Weight

Mass (kDA):
22.357 kDA

Genomic Context


Human

Location:	18q21.33
Sequence:	18; NC_000018.10 (61808067..61894420, complement)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Lysosome membrane; Single-pass membrane protein.

PTMs

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RNF152

References

PMID: 21203937 by Zhang S., et al. RNF152, a novel lysosome localized E3 ligase with pro-apoptotic activities.

PMID: 25936802 by Deng L., et al. The ubiquitination of RagA GTPase by RNF152 negatively regulates mTORC1 activation.