This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Ribonuclease 7.
Causes loss of bacterial membrane integrity (PubMed:17150966). Probably contributes to urinary tract sterility (PubMed:25075772).
Human | |
---|---|
Gene Name: | RNASE7 |
Uniprot: | Q9H1E1 |
Entrez: | 84659 |
Belongs to: |
---|
pancreatic ribonuclease family |
EC 3.1.27; EC 3.1.27.-; EC 3.1.27.5; MGC133220; ribonuclease 7; ribonuclease, RNase A family, 7; RNase 7; SAP-2; Skin-derived antimicrobial protein 2
Mass (kDA):
17.419 kDA
Human | |
---|---|
Location: | 14q11.2 |
Sequence: | 14; NC_000014.9 (21042362..21044233) |
Expressed in collecting ducts in kidney, and in apical uroepithelium in bladder (at protein level) (PubMed:25075772). Expressed in various epithelial tissues including skin, respiratory tract, genito-urinary tract and, at a low level, in the gut (PubMed:12244054). Expressed in liver, kidney, skeletal muscle and heart (PubMed:12527768).
Secreted. Detected in urine.
PMID: 12244054 by Harder J., et al. RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin.
PMID: 12527768 by Zhang J., et al. Human RNase 7: a new cationic ribonuclease of the RNase A superfamily.