Protein dpy-30 homolog (Dpy30)

As part of the MLL1/MLL complex, involved in the methylation of histone H3 in'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.

May play some role in histone H3 acetylation. In embryonic stem cells (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and histone H3'Lys- 4' methylation at key developmental loci, including that mediated by retinoic acid.