Ras and Rab interactor 1 Antibodies

AND RIN1 ELISA kits, Ras and Rab interactor 1 Proteins

Many biological assays use antibodies to detect Ras and Rab interactor 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ras and Rab interactor 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ras and Rab interactor 1 antibodies...

We validate the specificity of these antibodies to Ras and Rab interactor 1 by testing them on tissues known to express RIN1 positively and negatively. Browse below to find the RIN1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RIN1 Infographic by Boster Bio

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Anti-Ras and Rab interactor 1 RIN1 Antibody

13 Q&As

Human, Mouse, Rat

$360
Cat # A04953
100 µl

Anti-RIN1 Antibody Picoband®

Human

ELISA, Flow Cytometry, WB

$370
Cat # A04953-1
100 µg/vial

RIN1 Overview

Facts about Ras and Rab interactor 1.

RIN1 3D structure. Source: alphafold

Ras and Rab interactor 1 (RIN1)

Ras effector protein, which might function as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at various levels.

First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling.

Gene Information

Human
Gene Name:	RIN1
Uniprot:	Q13671
Entrez:	9610

Family

Belongs to:

RIN (Ras interaction/interference) family

Alternative Names

Ras and Rab interactor 1; ras inhibitor 1; Ras inhibitor JC99; ras inhibitor RIN1; Ras interaction/interference protein 1

Molecular Weight

Mass (kDA):
84.099 kDA

Genomic Context


Human

Location:	11q13.2
Sequence:	11; NC_000011.10 (66330241..66336774, complement)

Tissue Specificity

Expressed in all tissues examined with high levels in brain, placenta and pancreas.

Subcellular Localizations

Cytoplasm. Membrane. Cytoplasm, cytoskeleton. Some amount is membrane-associated.

Diseases

Malignant Neoplasms
Neoplasms
Cell Transformation, Neoplastic
Leukemia
Myeloid Leukemia
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Myeloid Leukemia, Chronic
Metaplastic Cell Transformation
Stomach Neoplasms
Carcinoma
Metastatic Malignant Neoplasm To The Lymph Node

Malignant Tumor Of Colon
Neoplasm Invasiveness
Adenocarcinoma
Non-small Cell Lung Carcinoma
Colorectal Neoplasms
Chromosomal Translocation
Colonic Neoplasms

Interacting Proteins

ABL1
ABL2
CALCOCO2
EGFR
HRAS

LZTS2
NRAS
RRAS2
STAM2

Pathways

Endocytosis
Localization
Cell Proliferation
Cell Migration
Rna Interference
Cell Motility
Cell Differentiation
Receptor-mediated Endocytosis
Cell Growth
Cell Adhesion
Cell Activation
Gene Silencing
Regulation Of Signaling

T Cell Activation
Reverse Transcription
Axon Guidance
Cell Cycle
Long-term Memory
Interphase
Invasive Growth

PTMs

Phosphorylation
Demethylation

Cleavage
Methylation

Ubiquitination

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RIN1

References

PMID: 1849280 by Colicelli J., et al. Expression of three mammalian cDNAs that interfere with RAS function in Saccharomyces cerevisiae.

PMID: 7862125 by Han L., et al. A human protein selected for interference with Ras function interacts directly with Ras and competes with Raf1.