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- Table of Contents
Facts about Rab-interacting lysosomal protein.
Induces recruiting of dynein-dynactin motor complexes to Rab7A-containing late endosome and lysosome compartments. Promotes centripetal migration of phagosomes along with the fusion of phagosomes with the late endosomes and lysosomes.
Human | |
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Gene Name: | RILP |
Uniprot: | Q96NA2 |
Entrez: | 83547 |
Belongs to: |
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No superfamily |
rab-interacting lysosomal protein; PP10141; Rab interacting lysosomal protein
Mass (kDA):
44.2 kDA
Human | |
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Location: | 17p13.3 |
Sequence: | 17; NC_000017.11 (1646150..1650077, complement) |
Late endosome membrane. Lysosome membrane. Cytoplasmic vesicle, phagosome membrane. Associated with late endosomal, lysosomal and phagosomal membranes. The interaction with RAB7A is necessary for its recruitment to phagosomes.
PMID: 11179213 by Cantalupo G., et al. Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes.
PMID: 11520070 by Bucci C., et al. Expression analysis and chromosomal assignment of PRA1 and RILP genes.