Synembryn-B Antibodies

AND RIC8B ELISA kits, Synembryn-B Proteins

Many biological assays use antibodies to detect Synembryn-B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Synembryn-B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Synembryn-B antibodies...

We validate the specificity of these antibodies to Synembryn-B by testing them on tissues known to express RIC8B positively and negatively. Browse below to find the RIC8B antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RIC8B Infographic by Boster Bio

All RIC8B Products

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Applications

Price

RIC8 (RIC8B) (NM_018157) Human Recombinant Protein

$813
Cat # PROTQ9NVN3
20 µg

RIC8 (RIC8B) (NM_018157) Human Over-expression Lysate

Human

$960
Cat # LS055188
100 µg

RIC8B Overview

Facts about Synembryn-B.

RIC8B 3D structure. Source: alphafold

Synembryn-B (RIC8B)

Guanine nucleotide exchange factor (GEF), which may trigger a few, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Willing to potentiate G(olf)-alpha-dependent cAMP accumulation suggesting that it may be an important element for odorant signal transduction.

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Gene Information

Human
Gene Name:	RIC8B
Uniprot:	Q9NVN3
Entrez:	55188

Family

Belongs to:

synembryn family

Alternative Names

Brain synembrin; hSyn; Protein Ric-8B; RIC8; RIC8B resistance to inhibitors of cholinesterase 8 homolog B (C. elegans); synembryn; synembryn-B

Molecular Weight

Mass (kDA):
58.825 kDA

Genomic Context


Human

Location:	12q23.3
Sequence:	12; NC_000012.12 (106774621..106889316)

Subcellular Localizations

Cytoplasm, cell cortex. Localizes to the cell cortex.

Pathways

Cell Division
Membrane Depolarization
Osteoblast Differentiation
Regulation Of Cell Division

PTMs

Ubiquitination

Myristoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RIC8B

References

PMID: 12652642 by Klattenhoff C., et al. Human brain synembryn interacts with Gsalpha and Gqalpha and is translocated to the plasma membrane in response to isoproterenol and carbachol.