RIC1 Antibodies

AND RIC1 ELISA kits, RIC1 Proteins

Many biological assays use antibodies to detect RIC1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RIC1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RIC1 antibodies...

We validate the specificity of these antibodies to RIC1 by testing them on tissues known to express RIC1 positively and negatively. Browse below to find the RIC1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RIC1 Infographic by Boster Bio

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KIAA1432 (RIC1) (NM_020829) Human Over-expression Lysate

Human

$960
Cat # LS057589
100 µg

RIC1 Overview

Facts about RAB6A-GEF complex partner protein 1.

RIC1 3D structure. Source: alphafold

RAB6A-GEF complex partner protein 1 (RIC1)

The RIC1-RGP1 complex functions as a guanine nucleotide exchange factor (GEF), which triggers RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1- RGP1 complex participates in the recycling of mannose-6-phosphate receptors.

Required for phosphorylation and localization of GJA1. .

Gene Information

Human
Gene Name:	RIC1
Uniprot:	Q4ADV7
Entrez:	57589

Family

Belongs to:

RIC1 family

Alternative Names

BA207C16.1; CIP150; Connexin 43-Interacting Protein 150 KDa; Connexin-43-Interacting Protein Of 150 KDa; Protein RIC1 Homolog; RAB6A GEF Complex Partner 1; RIC1 Homolog, RAB6A GEF Complex Partner 1; RIC1

Molecular Weight

Mass (kDA):
159.301 kDA

Genomic Context


Human

Location:	9p24.1
Sequence:	9; NC_000009.12 (5629030..5778633)

Tissue Specificity

Present in kidney and various cell lines (at protein level). Widely expressed at low level.

Subcellular Localizations

Cytoplasm, cytosol. Membrane; Single-pass membrane protein.

Diseases

Malignant Squamous Cell Neoplasm
Cell Transformation, Neoplastic
Malignant Neoplasms
Malignant Neoplasm Of Breast
Mammary Neoplasms
Carcinoma

Pathways

Methylation
Cell Proliferation
Protein Targeting
Dna Methylation
Histone Modification
Histone Methylation

Localization

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RIC1

References

PMID: 16112082 by Akiyama M., et al. Molecular cloning and functional analysis of a novel Cx43 partner protein CIP150.

PMID: 23091056 by Pusapati G.V., et al. Ric1-Rgp1 complex is a guanine nucleotide exchange factor for the late Golgi Rab6A GTPase and an effector of the medial Golgi Rab33B GTPase.