RHOJ Antibodies

AND RHOJ ELISA kits, RHOJ Proteins

Many biological assays use antibodies to detect RHOJ, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RHOJ in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RHOJ antibodies...

We validate the specificity of these antibodies to RHOJ by testing them on tissues known to express RHOJ positively and negatively. Browse below to find the RHOJ antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RHOJ Infographic by Boster Bio

All RHOJ Products

Product

Figures

Specificity

Applications

Price

Anti-RHOJ Antibody

Human, Mouse

ELISA, WB

$380
Cat # A09259
100ul

RHOJ (NM_020663) Human Recombinant Protein

$1249
Cat # PROTQ9H4E5
20 µg

Anti-RHOJ Mouse Monoclonal Antibody [Clone ID: OTI1D7]

+10

Human, Mouse, Rat

IF, IHC, WB

$523
Cat # M09259
100 µl

RHOJ (NM_020663) Human Over-expression Lysate

Human

$628
Cat # LS057381
100 µg

RHOJ Overview

Facts about Rho-related GTP-binding protein RhoJ.

RHOJ 3D structure. Source: alphafold

Rho-related GTP-binding protein RhoJ (RHOJ)

Plasma membrane-associated small GTPase especially involved in angiogenesis (PubMed:21628409, PubMed:24434213, PubMed:30158707). Required for endothelial cell migration during vascular development via its interaction with GLUL (PubMed:30158707).

Elicits the formation of F-actin-rich structures, thereby regulating endothelial cell migration (PubMed:30158707). .

Gene Information

Human
Gene Name:	RHOJ
Uniprot:	Q9H4E5
Entrez:	57381

Family

Belongs to:

small GTPase superfamily

Alternative Names

ARHJTC10B; FLJ14445; ras homolog gene family, member J; RASL7B; Ras-like protein family member 7B; RAS-like, family 7, member B; RHOI; rho-related GTP-binding protein RhoJ; Tc10-like GTP-binding protein; TC10-like Rho GTPase; TCLMGC34777

Molecular Weight

Mass (kDA):
23.821 kDA

Genomic Context


Human

Location:	14q23.2
Sequence:	14; NC_000014.9 (63204412..63293508)

Tissue Specificity

Specifically expressed in endothelial cells in different tissues, such as brain, heart, lung and liver.

Subcellular Localizations

Cell membrane; Lipid-anchor; Cytoplasmic side. Localization to the plasma membrane is regulated by GLUL.

Diseases

Hypoxia
Tumor Angiogenesis
Neoplasms
Pathologic Neovascularization
Stomach Neoplasms
Vertigo
Melanoma
Sarcoma
Carcinoma
Malignant Neoplasms
Mycobacterium Infections, Nontuberculous

Cytomegalovirus Infections
Retinal Diseases
Bacterial Infections
Carcinoma, Lewis Lung
Anoxia
Mycobacterium Marinum Infection

Interacting Proteins

BHLHE40
BLZF1
CDC42EP1
GLUL
MEOX2

PAK2
PAK6
PARD6B
SSX3
TRIP10

WASL

Pathways

Cell Migration
Tube Formation
Localization
Cell Cycle
Angiogenesis
Cell Proliferation
Immune Response
Fibroblast Migration
Endothelial Cell Migration
Cell Division
Regeneration

Flight
Chemotaxis
Cell Death
Chromatin Modification
Pathogenesis
Rna Interference

PTMs

Phosphorylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RHOJ

References

PMID: 10967094 by Vignal E., et al. Characterization of TCL, a new GTPase of the Rho family related to TC10 and Cdc42.

PMID: 21628409 by Yuan L., et al. RhoJ is an endothelial cell-restricted Rho GTPase that mediates vascular morphogenesis and is regulated by the transcription factor ERG.