RHOC Antibodies

AND RHOC ELISA kits, RHOC Proteins

Many biological assays use antibodies to detect RHOC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RHOC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RHOC antibodies...

We validate the specificity of these antibodies to RHOC by testing them on tissues known to express RHOC positively and negatively. Browse below to find the RHOC antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RHOC Infographic by Boster Bio

All RHOC Products

Product

Figures

Specificity

Applications

Price

RHOC (NM_001042678) Human Recombinant Protein

$1249
Cat # PROTP08134
20 µg

Anti-RHOC Mouse Monoclonal Antibody [Clone ID: OTI3A5]

Human, Mouse, Rat

IHC, WB

$523
Cat # M01211
100 µl

RHOC (NM_175744) Human Over-expression Lysate

Human

$628
Cat # LS000389
100 µg

RHOC Overview

Facts about Rho-related GTP-binding protein RhoC.

RHOC 3D structure. Source: alphafold

Rho-related GTP-binding protein RhoC (RHOC)

Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent sign that's needed for the myosin contractile ring formation during cell cycle cytokinesis.

Regulates apical junction formation in bronchial epithelial cells. .

Gene Information

Human
Gene Name:	RHOC
Uniprot:	P08134
Entrez:	389

Family

Belongs to:

small GTPase superfamily

Alternative Names

ARH9ARHCRho cDNA clone 9; H9; MGC1448; MGC61427; oncogene RHO H9; ras homolog gene family, member C; RAS-related homolog 9; rhoC GTPase; RhoC; RHOH9; rho-related GTP-binding protein RhoC; small GTP binding protein RhoC

Molecular Weight

Mass (kDA):
22.006 kDA

Genomic Context


Human

Location:	1p13.2
Sequence:	1; NC_000001.11 (112701127..112707403, complement)

Subcellular Localizations

Cell membrane; Lipid-anchor; Cytoplasmic side. Cleavage furrow. Translocates to the equatorial region before furrow formation in a ECT2-dependent manner.

Diseases

Malignant Neoplasms
Neoplasms
Neoplasm Metastasis
Cell Invasion
Neoplasm Invasiveness
Carcinoma
Mammary Neoplasms
Malignant Neoplasm Of Breast
Malignant Paraganglionic Neoplasm
Inflammatory Breast Carcinoma
Melanoma
Tissue Adhesions

Cell Transformation, Neoplastic
Lung Neoplasms
Tumor Angiogenesis
Lymphatic Metastasis
Liver Carcinoma
Malignant Squamous Cell Neoplasm
Liver Neoplasms

Interacting Proteins

RIPOR2

Pathways

Cell Migration
Cell Motility
Angiogenesis
Cell Proliferation
Localization
Cell Growth
Cell Cycle
Rna Interference
Cell Adhesion
Pathogenesis
Prenylation
Cytoskeleton Organization
Translation

Wound Healing
Secretion
Cytokinesis
Cell Differentiation
Lymphangiogenesis
Reverse Transcription
Membrane Organization

PTMs

Phosphorylation
Ribosylation
Farnesylation

Geranylgeranylation
Prenylation
Methylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RHOC

References

PMID: 3283705 by Chardin P., et al. Coding sequence of human rho cDNAs clone 6 and clone 9.

PMID: 8816443 by Leung T., et al. The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton.