RHOB Antibodies

Rho-related GTP-binding protein RhoB (RHOB)

Mediates apoptosis in neoplastically transformed cells after DNA damage. Not vital for growth but affects cell adhesion and growth factor signaling in transformed cells.

Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a range of proteins.

Gene Information

Human
Gene Name:	RHOB
Uniprot:	P62745
Entrez:	388

Family

Belongs to:
small GTPase superfamily

Alternative Names

ARH6MSTP081; ARHBAplysia RAS-related homolog 6; h6; MST081; oncogene RHO H6; ras homolog gene family, member B; Rho cDNA clone 6; RHOH6RhoB; rho-related GTP-binding protein RhoB

Molecular Weight

Mass (kDA):
22.123 kDA

Genomic Context

Human
Location:	2p24.1
Sequence:	2; NC_000002.12 (20447074..20449440)

Subcellular Localizations

Late endosome membrane; Lipid-anchor. Cell membrane; Lipid-anchor. Nucleus. Cleavage furrow. Late endosomal membrane (geranylgeranylated form). Plasma membrane (farnesylated form). Also detected at the nuclear margin and in the nucleus. Translocates to the equatorial region before furrow formation in a ECT2-dependent manner.

Diseases

• Malignant Neoplasms
• Neoplasms
• Tissue Adhesions
• Genotoxic Stress
• Cell Transformation, Neoplastic
• Crest Syndrome
• Degenerative Polyarthritis
• Malignant Neoplasm Of Breast
• Carcinoma
• Neoplasm Metastasis
• Malignant Paraganglionic Neoplasm
• Cell Invasion
• Lung Neoplasms

• Alzheimer's Disease
• Malignant Tumor Of Colon
• Neoplasm Invasiveness
• Mammary Neoplasms
• Shwachman Syndrome
• Colonic Neoplasms
• Malignant Neoplasm Of Lung

Interacting Proteins

• TNFAIP1

Pathways

• Cell Cycle
• Cell Growth
• Cell Proliferation
• Localization
• Cell Adhesion
• Translation
• Cell Death
• Delamination
• Cell Migration
• Sensitization
• Dna Replication
• S Phase
• Pathogenesis

• Cell Activation
• Regulation Of Binding
• Dna Hypomethylation
• T Cell Activation
• Aging
• Immune Response
• Dna Demethylation

PTMs

• Ribosylation
• Phosphorylation
• Geranylgeranylation

• Prenylation
• Demethylation
• Methylation

Research Areas

• Angiogenesis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RHOB

Boster Bio - Best Uses Of The RHOB Marker

The RHOB Marker is a highly cited protein in the research community. Boster has been a leading provider of high-affinity prima antibodies for over 25 years. These antibodies have been validated by the research community. They can also be manufactured in the United States. Listed below are some of the most common uses of this marker. Want to learn more? Continue reading.

Research community is highly cited on Boster's primary antibodies

Boster's primary antibody products are often cited in the scientific community as they have high affinity. These antibodies are highly valuable resources for researchers because they have been validated for Western Blotting, Immunohistochemistry, and ELISA experiments. The company offers antibodies of all reactivity levels and species. The company offers primary antibodies that last more than 25 years.

ANTI-MOUSE/HUMAN MAC-2 antibody (GALECTIN-33) and Mouse Anti-Human TRA-1-60 stainAlive? are two of Boster's primary antibodies. Antibody. Other highly cited antibodies include ANTIHUMAN MAC-2 MAC-2 HTATIP HTATIP HTATIP HTATIP HTATIP HTATIP HTATIP HTATIP, HTATIP, HTATIP, Mouse Anti-Peroxiredoxin-3 & Anti-VSVM virus.

They can be purchased from Bioss Biotechnology Co., Ltd.

Boster Biologicals was created by Steven Boster (a Chinese entrepreneur and scientist who has a passion for science). It is a leading supplier in immunological reagents for neurosciences, cancer, inflammation, and IHC. With picogram-level sensitivity, these kits can detect biomarkers in a wide variety of samples. They can also be ordered through tebu–bio.

RHOB acts as a suppressor and negative modifier of cancer progression. It is produced by Shanghai GenePharma Co. Ltd.. You can get it from Bioss Biotechnology Co. Ltd. Beijing. Abcam and Bioss Biotechnology Co. Ltd. also sell this antibody. There are many other companies that sell anti MMP antibody products, such abcam.

They are manufactured in America

The company was started in 1993 by a single product, an IHC-optimized Polyclonal Antibody. They were China’s largest catalog anti-body company by the end of the 1990s. Boster Bio later developed PicoKine(tm), a proprietary ELISA technology for high-sensitivity ELISA tests. This proprietary platform is highly specific and has been validated against 250 tissues, untransfected cell lines, and recombinant proteins.

The company manufactures a variety of ELISA and research antibodies to detect biomarkers in various areas such as cancer, neurosciences and inflammation. Their products can detect molecules up to a picogram in sensitivity and are supported by tebubio's technical support. The company also manufactures ELISA kits that include secondary antibody, including Picoband.