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Transforming protein RhoA Antibodies
AND RHOA ELISA kits, Transforming protein RhoA Proteins
Many biological assays use antibodies to detect Transforming protein RhoA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Transforming protein RhoA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Transforming protein RhoA antibodies...
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RHOA Infographic by Boster Bio
All RHOA Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M00207-2
100 μl
Cat # M00207-2
100 μl
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # M00207
100 μl
Cat # M00207
100 μl
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00207-1
100 μl
Cat # M00207-1
100 μl
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$405
Cat # A00207-2
100ul
Cat # A00207-2
100ul
RHOA Overview
Facts about Transforming protein RhoA.
Transforming protein RhoA (RHOA)
Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis.
Plays an important role in cleavage furrow formation. Stimulates PKN2 kinase activity.
Gene Information
| Human | |
|---|---|
| Gene Name: | RHOA |
| Uniprot: | P61586 |
| Entrez: | 387 |
Family
| Belongs to: |
|---|
| small GTPase superfamily |
Alternative Names
h12; oncogene RHO H12; ras homolog gene family, member A; Rho cDNA clone 12; RHO12; RhoA; RHOH12ARH12ARHAAplysia ras-related homolog 12; small GTP binding protein RhoA; transforming protein RhoA
Molecular Weight
Mass (kDA):
21.768 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p21.31 |
| Sequence: | 3; NC_000003.12 (49359145..49411976, complement) |
Subcellular Localizations
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton. Cleavage furrow. Cytoplasm, cell cortex. Midbody. Cell projection, lamellipodium. Cell projection, dendrite. Localized to cell-cell contacts in calcium-treated keratinocytes (By similarity). Translocates to the equatorial region before furrow formation in a ECT2-dependent manner. Localizes to the equatorial cell cortex (at the site of the presumptive furrow) in early anaphase in an activated form and in a myosin- and actin-independent manner.
Diseases
- Tissue Adhesions
- Malignant Neoplasms
- Neoplasms
- Cell Invasion
- Neoplasm Metastasis
- Carcinoma
- Neoplasm Invasiveness
- Hypertensive Disease
- Inflammation
- Cell Transformation, Neoplastic
- Pathologic Vasoconstriction
- Nervousness
- Tumor Angiogenesis
Interacting Proteins
- AGER
- ARHGAP1
- ARHGDIA
- ARHGEF11
- ARHGEF12
- ARHGEF19
- CDKN1B
- DAAM1
- DIAPH1
- Diaph1
Pathways
- Cell Migration
- Localization
- Cell Proliferation
- Cell Adhesion
- Cell Motility
- Cell Cycle
- Secretion
- Pathogenesis
- Cell Growth
- Cytokinesis
- Sensitization
- Angiogenesis
- Regeneration
PTMs
- Phosphorylation
- Ribosylation
- Prenylation
- Cleavage
- Geranylgeranylation
- Dephosphorylation
- Farnesylation
- Methylation
- Ubiquitination
- Deamidation
Research Areas
- Cancer
- mTOR Pathway
- Signal Transduction
- Wnt Signaling Pathway
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RHOA
bosterbio.com/bosterbio-gene-info-cards/RHOA
References
PMID: 3822842 by Yeramian P., et al. Nucleotide sequence of human rho cDNA clone 12.
PMID: 7835413 by Fagan K.P., et al. Sequence of rho small GTP-binding protein cDNAs from human retina and identification of novel 5' end cloning artifacts.
1 Publications of Boster Transforming protein RhoA Antibodies & ELISA Kits
- PubMed ID: 10.12659/MSM.907277, Rho Kinase Type 1 (ROCK1) Promotes Lipopolysaccharide-induced Inflammation in Co...
*More publications can be found for each product on its corresponding product page