Rgmb Antibodies

RGM domain family member B (Rgmb)

Member of the repulsive guidance molecule (RGM) family that leads to the patterning of the developing nervous system. Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling.

Promotes neuronal adhesion. May inhibit neurite outgrowth (By similarity).

Gene Information

Mouse
Gene Name:	Rgmb
Uniprot:	Q7TQ33
Entrez:	68799

Family

Belongs to:
repulsive guidance molecule (RGM) family

Alternative Names

DKFZp434P228; Dragon; DRG11-responsive axonal guidance and outgrowth of neurite; RGM domain family, member B; RGMB; RGM-B

Molecular Weight

Mass (kDA):
47.181 kDA

Genomic Context

Mouse
Location:	17|17 A2
Sequence:	17;

Tissue Specificity

Detected in neonatal and adult dorsal root ganglion sensory neurons, spinal cord, and brain (at protein level). Also expressed at high levels in retinal ganglion cells of developing mouse, extending to the optic nerve (at protein level). Expressed in testis, epididymis, ovary, uterus, and pituitary.

Diseases

• Nervousness
• Malignant Neoplasms
• Tissue Adhesions
• Malignant Neoplasm Of Breast
• Mammary Neoplasms
• Prostatic Neoplasms
• Hemochromatosis
• Neoplasm Metastasis
• Bone Neoplasms
• Neoplasm Invasiveness
• Degenerative Polyarthritis
• Growth Acceleration

• Osteosarcoma
• Neoplasms
• Metastatic Malignant Neoplasm To The Bone
• Rheumatoid Arthritis
• Cell Invasion
• Malignant Neoplasm Of Prostate
• Neoplasm Recurrence, Local

Pathways

• Cell Migration
• Pathogenesis
• Cell Adhesion
• Neural Tube Closure
• Cell Proliferation
• Axon Regeneration
• Cell-matrix Adhesion
• Regeneration
• Tube Closure

• Flight
• Cell Cycle
• Axon Guidance
• Cell Growth

PTMs

• Autocatalytic cleavage
• Disulfide bond

• Glycoprotein
• GPI-anchor

• Lipoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Rgmb

Best Uses Of The RGMB Marker From Boster Bio

We will discuss the many reasons why researchers trust primary antibodies from Boster Bio. Find out more about Boster's products and applications. You can trust Boster primary antibodies for your next experiment. Learn more about Boster Bio’s RGMB marker. You can also read our articles about the quality of our products. We will discuss the products that we offer and the best uses for our antibodies.

The research community trusts Boster's primary antibody.

Boster's antibodies have a reputation for being highly specific and affinity. These antibodies have been extensively used by more than 29,000 publications, which demonstrates their high sensitivity as well as specificity. Furthermore, Boster's antibodies are widely used for many applications, including immunohistochemistry, Western Blotting, and ELISA. Boster also offers secondary antibodies free of charge for all primary antibodies.

The reproducibility of antibody data has been under scrutiny in the scientific community. PROGEN has created a quality initiative to address the needs and expectations of the research community. To help researchers determine which antibodies have the highest quality, PROGEN also analyzes hundreds and thousands of antibody citations. This allows customers to choose the products with confidence, based on the high-quality and high-reliability data provided by their antibody suppliers.

Boster's antibodies are trusted by researchers due to their strict quality standards. Boster's products are manufactured by the top manufacturers in the world, and they have been lauded as the best. The company is ISO 9001 accredited, which means it meets high quality standards. These high-quality antibodies can be used for immunocytochemistry. The research results are reliable, which is essential for drug development.

Rockland's antibodies are one of the many primary antibodies that are available for research. They can be used in a variety of applications. These antibodies recognize certain antigens with high specificity, affinity, and affinity. These antibodies do not contain secondary antibodies. These antibodies can give a lower-than optimal signal because they are not compatible with the way tissues are preserved. Therefore, it is important to remember that RNA binding proteins can silence mRNA before translation.

Products

RGMB is a member the repulsive guide molecule (RGM), which is represented by MIM 607362 gene. It plays an important part in the development of the nervous system. It coordinates bone-morphogenetic signals and has been implicated for cancer. A low level of expression can be associated with poor prognosis. For more information on this gene and its products, please read the following.

Applications

The RGMB Marker belongs to the family of Repulsive Guidance Molecules (RGMs), which play a role in the patterning of the developing nervous system. They also coordinate bone-morphogenetic protein signals and may be a regulator in cancer. Poor prognosis is linked to the inability to express RGMs. This article will discuss a few of the applications of this marker.