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- Table of Contents
Facts about Transcription factor RFX3.
Required for the biogenesis of motile cilia by regulating growth and beating efficiency of motile cells. Also required for ciliated ependymal cell differentiation.
Human | |
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Gene Name: | RFX3 |
Uniprot: | P48380 |
Entrez: | 5991 |
Belongs to: |
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RFX family |
bA32F11.1; DNA binding protein RFX3; MGC87155; Regulatory factor X 3; regulatory factor X, 3 (influences HLA class II expression); transcription factor RFX3
Mass (kDA):
83.53 kDA
Human | |
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Location: | 9p24.2 |
Sequence: | 9; NC_000009.12 (3218297..3526529, complement) |
Nucleus.
PMID: 8289803 by Reith W., et al. RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins.
PMID: 10330134 by Iwama A., et al. Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains.