DNA-binding protein RFX5 Antibodies

AND RFX5 ELISA kits, DNA-binding protein RFX5 Proteins

Many biological assays use antibodies to detect DNA-binding protein RFX5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DNA-binding protein RFX5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DNA-binding protein RFX5 antibodies...

We validate the specificity of these antibodies to DNA-binding protein RFX5 by testing them on tissues known to express RFX5 positively and negatively. Browse below to find the RFX5 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RFX5 Infographic by Boster Bio

All RFX5 Products

Product

Figures

Specificity

Applications

Price

Anti-DNA-binding protein RFX5 RFX5 Antibody

4 Q&As

Human

$599
Cat # A05527
100uL

RFX5 Overview

Facts about DNA-binding protein RFX5.

RFX5 3D structure. Source: alphafold

DNA-binding protein RFX5 (RFX5)

Activates transcription from class II MHC promoters. Recognizes X-boxes.

Mediates cooperative binding between RFX and NF-Y. RFX binds the X1 box of MHC-II promoters.

Gene Information

Human
Gene Name:	RFX5
Uniprot:	P48382
Entrez:	5993

Family

Belongs to:

RFX family

Alternative Names

DNA-binding protein RFX5; Regulatory factor X 5; regulatory factor X, 5 (influences HLA class II expression)

Molecular Weight

Mass (kDA):
65.323 kDA

Genomic Context


Human

Location:	1q21.3
Sequence:	1; NC_000001.11 (151340640..151347319, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Nucleus.

Diseases

Immunologic Deficiency Syndromes
Bare Lymphocyte Syndrome
Severe Combined Immunodeficiency
Congenital Combined Immunodeficiency
Primary Immune Deficiency Disorder
Infective Disorder
Inflammation
Burkitt Lymphoma
Malignant Neoplasms
Neoplasms
Chlamydia Infections

Dental Plaque
Atherosclerosis
Pneumonia
Fibrosarcoma
Hereditary Diseases
Chronic Inflammation

Interacting Proteins

HDAC2

Pathways

Immune Response
Localization
Methylation
Adaptive Immune Response
Cell Activation
T Cell Activation
Dna Methylation
Nuclear Export
Mismatch Repair
Histone Acetylation
Nuclear Import
Transport
Protein Phosphorylation

Regulation Of Gene Expression
Dna Excision
Cytokine Production
Antigen Processing And Presentation
Intraflagellar Transport
Rna Interference
Secretion

PTMs

Acetylation
Methylation

Phosphorylation
Deacetylation

Cleavage

Research Areas

Adaptive Immunity
Immunology

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RFX5

References

PMID: 7744245 by Steimle V., et al. A novel DNA-binding regulatory factor is mutated in primary MHC class II deficiency (bare lymphocyte syndrome).

PMID: 10072068 by Nagarajan U.M., et al. RFX-B is the gene responsible for the most common cause of the bare lymphocyte syndrome, an MHC class II immunodeficiency.