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- Table of Contents
Facts about MHC class II regulatory factor RFX1.
Also binds to an inverted repeat (ENH1) necessary for hepatitis B virus genes expression and into the most upstream element (alpha) of the RPL30 promoter. .
Human | |
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Gene Name: | RFX1 |
Uniprot: | P22670 |
Entrez: | 5989 |
Belongs to: |
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RFX family |
EFC; EF-C; Enhancer factor C; MHC class II regulatory factor RFX; MHC class II regulatory factor RFX1; Regulatory factor X 1; regulatory factor X, 1 (influences HLA class II expression); RFX; trans-acting regulatory factor 1; Transcription factor RFX1
Mass (kDA):
104.758 kDA
Human | |
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Location: | 19p13.12 |
Sequence: | 19; NC_000019.10 (13961530..14007514, complement) |
Nucleus.
PMID: 2253877 by Reith W., et al. MHC class II regulatory factor RFX has a novel DNA-binding domain and a functionally independent dimerization domain.
PMID: 8413236 by Siegrist C.A., et al. RFX1 is identical to enhancer factor C and functions as a transactivator of the hepatitis B virus enhancer.