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- Table of Contents
Facts about Tumor necrosis factor receptor superfamily member 19L.
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Human | |
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Gene Name: | RELT |
Uniprot: | Q969Z4 |
Entrez: | 84957 |
Belongs to: |
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RELT family |
Receptor expressed in lymphoid tissues; RELT tumor necrosis factor receptor; RELT; TNFRSF19L; TNFRSF19LFLJ14993; tumor necrosis factor receptor superfamily member 19L; tumor necrosis factor receptor superfamily, member 19-like
Mass (kDA):
46.092 kDA
Human | |
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Location: | 11q13.4 |
Sequence: | 11; NC_000011.10 (73376395..73397474) |
Spleen, lymph node, brain, breast and peripheral blood leukocytes (at protein level) (PubMed:28688764). Expressed highly in bone marrow and fetal liver. Very low levels in skeletal muscle, testis and colon. Not detected in kidney and pancreas.
Cell membrane; Single-pass type I membrane protein. Cytoplasm. Cytoplasm, perinuclear region.
PMID: 11313261 by Sica G.L., et al. RELT, a new member of the tumor necrosis factor receptor superfamily, is selectively expressed in hematopoietic tissues and activates transcription factor NF-kappaB.
PMID: 16530727 by Polek T.C., et al. The TNF receptor, RELT, binds SPAK and uses it to mediate p38 and JNK activation.