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- Table of Contents
Facts about Probable RNA-binding protein 19.
.
Human | |
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Gene Name: | RBM19 |
Uniprot: | Q9Y4C8 |
Entrez: | 9904 |
Belongs to: |
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RRM MRD1 family |
KIAA0682DKFZp586F1023; NPO; probable RNA-binding protein 19; RNA binding motif protein 19; RNA-binding motif protein 19
Mass (kDA):
107.332 kDA
Human | |
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Location: | 12q24.13-q24.21 |
Sequence: | 12; NC_000012.12 (113816740..113966371, complement) |
Expressed in the crypts of Lieberkuhn of the intestine and in intestinal neoplasia (at protein level).
Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm. Chromosome. In discrete foci distributed throughout the cytoplasm and nucleoplasm during the 4 to 8 cell stages and the morula stage, but not in the periphery of the nucleolar precursor body (NPB). During blastocyst development, becomes increasingly localized to the nucleolus and less to the cytoplasm. At the late blastocyst stage, localized predominantly in the nucleolus. Localized in the nucleolus during interphase and to the perichromosomal sheath during mitosis. Does not colocalize in the cytoplasm with GW182 in P-bodies. May translocate
PMID: 16027046 by Lorenzen J.A., et al. Rbm19 is a nucleolar protein expressed in crypt/progenitor cells of the intestinal epithelium.