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- Table of Contents
Facts about Splicing regulator RBM11.
May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1. .
Human | |
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Gene Name: | RBM11 |
Uniprot: | P57052 |
Entrez: | 54033 |
Belongs to: |
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No superfamily |
putative gene, RNA binding motif protein 11 like10putative RNA-binding protein 11; RNA binding motif protein 11; RNA-binding motif protein 11
Mass (kDA):
32.179 kDA
Human | |
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Location: | 21q11.2 |
Sequence: | 21; NC_000021.9 (14216107..14228372) |
Expressed in brain, hippocampus, prefrontal cortex, cerebellum, spinal cord, testis, mammary gland, spleen and kidney. Also expressed in fetal brain.
Nucleus, nucleoplasm. Nucleus speckle. Enriched in SRSF2-containing splicing speckles; shuttles between nucleoplasm and speckles.
PMID: 12036298 by Gardiner K., et al. Annotation of human chromosome 21 for relevance to Down syndrome: gene structure and expression analysis.
PMID: 12909339 by Brun M.-E., et al. Juxtacentromeric region of human chromosome 21: a boundary between centromeric heterochromatin and euchromatic chromosome arms.