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- Table of Contents
Facts about Histone-binding protein RBBP7.
These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZHtwo complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex. .
Human | |
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Gene Name: | RBBP7 |
Uniprot: | Q16576 |
Entrez: | 5931 |
Belongs to: |
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WD repeat RBAP46/RBAP48/MSI1 family |
G1/S transition control protein-binding protein RbAp46; Histone acetyltransferase type B subunit 2; histone-binding protein RBBP7; MGC138867; Nucleosome-remodeling factor subunit RBAP46; RbAp46; RBBP-7; retinoblastoma binding protein 7; Retinoblastoma-binding protein 7MGC138868; Retinoblastoma-binding protein p46; retinoblastoma-binding protein RbAp46
Mass (kDA):
47.82 kDA
Human | |
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Location: | Xp22.2 |
Sequence: | X; NC_000023.11 (16844341..16870362, complement) |
Nucleus.
PMID: 7503932 by Qian Y.-W., et al. Dual retinoblastoma-binding proteins with properties related to a negative regulator of ras in yeast.
PMID: 9150135 by Zhang Y., et al. Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex.