RASSF7 Antibodies

AND RASSF7 ELISA kits, RASSF7 Proteins

Many biological assays use antibodies to detect RASSF7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RASSF7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RASSF7 antibodies...

We validate the specificity of these antibodies to RASSF7 by testing them on tissues known to express RASSF7 positively and negatively. Browse below to find the RASSF7 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RASSF7 Infographic by Boster Bio

All RASSF7 Products

Product

Figures

Specificity

Applications

Price

Anti-RASSF7 Antibody

Human, Mouse

ELISA, IHC

$380
Cat # A09402
100ul

RASSF7 (NM_003475) Human Recombinant Protein

$1249
Cat # PROTQ02833
20 µg

RASSF7 (NM_003475) Human Over-expression Lysate

Human

$628
Cat # LS008045
100 µg

Anti-RASSF7 Antibody Picoband™

Human

ELISA, WB

$370
Cat # A09402-2
100 µg/vial

RASSF7 Overview

Facts about Ras association domain-containing protein 7.

RASSF7 3D structure. Source: alphafold

Ras association domain-containing protein 7 (RASSF7)

Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti- apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway.

Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization. .

Gene Information

Human
Gene Name:	RASSF7
Uniprot:	Q02833
Entrez:	8045

Family

Belongs to:

No superfamily

Alternative Names

chromosome 11 open reading frame 13; HRAS1-related cluster protein 1; HRAS1-related cluster-1; HRC1C11orf13HRAS1; MGC126069; MGC126070; Ras association (RalGDS/AF-6) domain family (N-terminal) member 7; Ras association (RalGDS/AF-6) domain family 7; ras association domain-containing protein 7

Molecular Weight

Mass (kDA):
39.945 kDA

Genomic Context


Human

Location:	11p15.5
Sequence:	11; NC_000011.10 (560970..564025)

Subcellular Localizations

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Colocalizes with gamma-tubulin.

Diseases

Malignant Neoplasms
Neoplasms
Cell Transformation, Neoplastic
Hypoxia
Carcinoma
Neuroblastoma
Liver Carcinoma
Allelic Imbalance
Endometrial Neoplasms
Endometrial Polyp
Myoclonic Epilepsies, Progressive
Hepatocarcinogenesis
Diabetes Mellitus

Epilepsy
Epilepsies, Myoclonic
Asthma
Diabetes Mellitus, Insulin-dependent
Endometrial Carcinoma
Liver Neoplasms
Myoclonus

Interacting Proteins

NCK2

Pathways

Methylation
Cell Death
Mitosis
Response To Stress
Cell Cycle
Response To Hypoxia
Dna Methylation
Cell Growth

Pathogenesis
Localization

PTMs

Methylation

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RASSF7

References

PMID: 1339391 by Weitzel J.N., et al. The HRAS1 gene cluster: two upstream regions recognizing transcripts and a third encoding a gene with a leucine zipper domain.

PMID: 20629633 by Recino A., et al. Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis.