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- Table of Contents
Facts about RAS protein activator like-3.
Functions as a Ras GTPase-activating protein.
Plays an essential role in the growth and functions of natural killer T (NKT) cells in the liver by negatively regulating RAS activity and the down-stream ERK signaling pathway..
Human | |
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Gene Name: | RASAL3 |
Uniprot: | Q86YV0 |
Entrez: | 64926 |
Belongs to: |
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No superfamily |
RAS Protein Activator Like 3; RAS Protein Activator Like-3
Mass (kDA):
111.898 kDA
Human | |
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Location: | 19p13.12 |
Sequence: | 19; NC_000019.10 (15451624..15464571, complement) |
Predominantly expressed in cells of hematopoietic lineages.
Cytoplasm. Cytoplasm, cell cortex.
PMID: 25652366 by Saito S., et al. RASAL3, a novel hematopoietic RasGAP protein, regulates the number and functions of NKT cells.